Open Positions

Research Fellow, Project Manager, Research Technologist and Research Coordinator

We are looking for dynamic, enthusiastic individuals with a background in biology, life sciences, physical sciences, computer sciences or medicine to join our cutting-edge translational research group.

Our openings are ideal for candidates interested in the interface between computational biology and medicine, offering the opportunity to interact with leaders in both fields in a uniquely dynamic environment with substantial opportunity for career development and growth. Prospective team members must enjoy taking on challenges, learning new platforms and analysis tools, working with a team, mentoring, and improving treatment for patients with brain disease.

Please see the job descriptions listed below for details.  If you are interested in applying for a position in the lab, please email your CV to info@strokegenomics.org 

 

Clinical Research Project Manager

GENERAL SUMMARY/ OVERVIEW STATEMENT: 

The Multi-Investigator Rosand, Anderson, and Biffi laboratories within the McCance Center for Brain Health, Department of Neurology, and Center for Genomic Medicine at Massachusetts General Hospital lead ambitious research programs in cerebrovascular disease, with the united goal of leveraging genomics, epidemiology, neuroimaging, clinical informatics, and machine learning to revolutionize the prevention of stroke and the preservation of brain health across the lifespan. With projects spread across Boston academic medical institutions and the Broad Institute, a diverse funding portfolio, and a dynamic staff of coordinators, technologists, data scientists, and research fellows, our research group serves as a hub for brain health research locally, nationally, and internationally.

We are looking for a well-organized, dynamic, highly motivated project manager to help us deliver on our near- and long-term research goals and manage our internal organizational programs in biobanking, data and sample management, and data visualization. Reporting to the Sr. Lab Manager and working closely with the principal investigators and scientific program director, the clinical research project manager will have responsibility for day-to-day and long-term strategic project management related to research programs of three principal investigators devoted to brain health. Responsibilities  include, but not limited to: ensuring research project deliverables are completed in a timely manner, ensuring seamless communication across project teams, supervising and task management/delegation for research coordinators and interns; management of regulatory activities associated with research studies, IRB submissions and renewals; assembling grant applications.

Well-developed organizational, communication and problem-solving abilities in a fast-paced research environment are required.  The ideal candidate must exhibit a high level of expertise, comfort, and independence in managing and facilitating objectives for a complex cross-functional project team that spans Mass General Brigham and external collaborations around the world. Previous experience with program and/or project management and a history of completing projects to specification is strongly preferred.

PRINCIPAL DUTIES AND RESPONSIBILITIES: 

Project Definition and Tracking

  • Track project progress and communicate with stakeholders
  • Prepare and disseminate communications with external stakeholders
  • Work closely with lab members to gain an understanding of data processing methods and tools
  • Documents and facilitates the definition of project scope, goals, and resource requirements
  • Translates clearly defined project needs into deliverables, milestones, and timelines by establishing the project plan
  • Tracks progress of key milestones, ensuring execution of key deliverables
  • Manages changes in timelines, deliverables and budget as needed
  • Works closely with project leaders to establish quality criteria and monitor quality of projects
  • Conducts project evaluations and assessment of results
  • Actively seeks out best practices; transmits this information to the project team and revises project plan accordingly
  • Develops timelines, task lists, and operational plans for the completion of research projects, grant deliverables, and laboratory management goals in coordination with the principal investigators.

Communication/Reporting

  • Ensures appropriate communication with all project stakeholders regarding timelines and status, deadlines, data requirements, logistics and all other project-related issues
  • Facilitates project meetings to continually align the team around goals and communicate blocking issues

Compliance

  • Ensures appropriate funds are in place and tracks financial status of all projects relative to available budgets
  • Works with Compliance office to generate and maintain appropriate IRB for work specific to project plan (if necessary)
  • Ensures that projects and activities adhere to institutional guidelines with regards to safety and regulatory compliance

Management and Teamwork

  • Delegates tasks to Clinical Research Coordinators, if necessary
  • Leads and develops agendas and minutes for meetings related to ongoing projects.
  • Identifies roadblocks and alternative strategies for the completion of projects on-time and to specification and communicates updated information on at-risk deliverables or deadlines to the Sr. Lab Manager and the principal investigators.
  • Develops detailed protocol documents that meet federal/institutional standards.
  • Ensures study design’s compatibility with clinical/research practices
  • Provides critical input as to feasibility of study design and available resources
  • Ensures document consistency.
  • Attends meetings and scientific conferences, as needed
  • Works with Data Manager and Coordinators to perform data audits, including quality control and assurance of research data, as need.
  • Assists with preparation of grant applications and manuscripts, including data analyses, literature searches, drafting of text, confirming affiliations and linking of funding to accepted manuscripts.
  • Assists with Material Transfer Agreements, Data Use Agreements and Research Collaboration agreements.
  • Maintains communication platforms including newsletters, emails, and lab websites/social media.
  • Assists with data collection, interviews, data analysis, and reporting of preliminary findings, as needed.

SKILLS/ABILITIES/COMPETENCIES REQUIRED: 

  • Demonstrated ability to work with a cross functional collaboration to effectively manage and deliver on project goals
  • Ability to adapt plans and priorities to rapidly shifting goals
  • Must possess a high level of initiative and the ability to work independently, as well as in a team environment
  • Highly detail oriented
  • Knowledge of project management techniques and tools
  • Excellent communication skills required; the ability to effectively communicate s information and influence others
  • Excellent time management, interpersonal, and organizational skills required
  • Must be able handle a variety of tasks and effectively solve problems as they arise
  • Excellent interpersonal/communications skills
  • Ability to make independent, effective decisions
  • Excellent judgement and ability to interpret information and protocol requirements
  • Aptitude for technical problem solving
  • Exceptional organizational skills and ability to organize time and priorities effectively, asking for direction when appropriate. Flexibility to handle multiple tasks and deadline pressures.
  • Ability to identify issues and initiates plans to address; Demonstrates forthrightness and integrity.
  • Skills to work efficiently and effectively and strives to do so in all aspects of position. Ability to engender these skills among staff.
  • Ability to handle sensitive and confidential matters discreetly and to ensure confidentiality guidelines are maintained by staff.
  • Ability to appropriately evaluate all aspects of a situation and to independently make appropriate and timely decisions.
  • Exceptional computer skills (including operating systems, word processing, database, electronic mail, Internet, and spreadsheets).
  • Knowledge in all aspects of laboratory safety and ability to ensure a safe environment for laboratory staff and subjects.
  • Ability to work with large groups of investigators across departments/centers and institutions to complete project deliverables
  • Innovative, detail-oriented and self-motivated

EDUCATION: 

  • Bachelor’s degree required; MA/MS/MPH preferred.

EXPERIENCE:                     

  • BS with 5+ years of related experience
  • Experience and training in project management or program management required
  • Experience in clinical research, neurological or genetic research, preferred.

SUPERVISORY RESPONSIBILITY                        

  • Indirect management of clinical research coordinators and lab technicians
  • Project management of clinical research coordinators, lab technicians, data managers, and research fellows

FISCAL RESPONSIBILITY

  • Fiscal responsibilities will include budgeting for projects, identifying cost-effective strategies to complete projects, and ensuring lab consumables are obtained at best rate possible.

WORKING CONDITIONS:

  • Remote work currently; office and lab environment upon return to onsite work.
  • Some local and international travel may be required
  • Some after-hours meetings may be required.
 

Research Fellow

The RosAnderson Lab is looking for a highly motivated individual with a background in genetics and/or data sciences to perform cutting-edge research utilizing genetic, epidemiological, and imaging data assembled from human subjects. Receiving general direction from Dr. Rosand, Dr. Anderson, and the Senior Research Lab Manager, the incumbent will work in the fields of complex disease genetics and bioinformatics to perform genetic and other analyses which include, but are not limited to; common and rare variant association testing, multivariate model-building using genetic and phenotypic data, sequencing and GWAS quality control and data harmonization, meta-analyses, prediction modeling, and genome annotation.  2-year minimum commitment is required.

The Research Fellow will be a project leader for execution of in silico analyses in the RosAnderson lab, working with the PIs, other fellows, and coordinator staff. The incumbent will also be responsible for digital curation of existing and future datasets and analyses, project management, the preparation of presentation materials, manuscripts and grant applications, mentoring of technologists and coordinators, and presentations at local, national and international conferences.

Skills and competencies required:

  • Time Management: Exceptional organizational skills and ability to organize time and priorities effectively, asking for direction when appropriate. Flexibility to handle multiple tasks and deadline pressures.
  • Analytical Skills: Ability to conceptualize and conduct complex analysis of research data
  • Capacity for independent work
  • Critical Thinking/Decision Making: Ability to appropriately evaluate all aspects of a situation and to independently make appropriate and timely decisions.
  • Interpersonal/communication: Excellent interpersonal/communications skills and a good command of English language, including medical and scientific terminology.
  • Information Systems/Technology Skills: Exceptional computer skills (including operating systems, word processing, database, electronic mail, Internet, and spreadsheets).
  • Experience with statistical and programming software (R, Python, C, SAS, SQL, Stata, Linux), preferred.

 

If interested in applying for this position, please email your CV/resume to info@strokegenomics.org

 

Clinical Research Coordinator I/II/Senior

OVERVIEW STATEMENT: 

The RosAnderson Laboratory in the Center for Genomic Medicine at Massachusetts General Hospital (MGH) is seeking a motivated, enthusiastic candidate to join their research group. We work in a rich multi-disciplinary environment involving clinicians, computational biologists, statisticians and geneticists both at MGH, the Broad Institute of Harvard and MIT as well as internationally through the International Stroke Genetics Consortium (ISGC)

Under the direction of the Senior Research Laboratory Manager, the Clinical Research Coordinator I/II/Sr. will work independently on ongoing research studies.  This includes project management of lab projects involving collaboration within and outside the lab and institution, organizing the receipt of DNA samples from collaborators within and outside the United States, collection of all phenotypic data associated with received samples, collection of and accurate recording of procedures and results, maintenance of the lab databases, maintaining lab stocks, participation in joint upkeep of the lab and participation and presenting at lab meeting. This position requires a person who has Bachelor of Science or Bachelor of Arts degree in molecular/cell biology or a related field, with great attention to detail, is capable of working independently after training, possesses good verbal and written communication skills, works well as part of a team and is comfortable corresponding with collaborators from all over the world.

PRINCIPAL DUTIES AND RESPONSIBILITIES

  • Collects & organizes patient data
  • Maintains records and databases
  • Uses software programs to generate graphs and reports
  • Obtains patient study data from medical records, physicians, etc.
  • Conducts library searches
  • Verifies accuracy of study forms
  • Updates study forms per protocol
  • Assists with interviewing study subjects
  • Administers and scores questionnaires
  • Performs study procedures, which may include phlebotomy, sample receipt, storage and tracking.
  • Assists with study regulatory submissions
  • Writes consent forms
  • Performs administrative support duties as required
  • Assists with project management of assigned studies
  • Day-to-day processing and handling of lab biospecimens (blood, saliva, CSF, plasma, DNA etc).
  • Sample tracking, inventory maintenance and retrieval of lab biospecimens.
  • Serve as rotating emergency contact for minus 80 freezers.
  • Curating the lab database and performing queries, when requested.
  • Prepares data and assists with analysis associated with lab projects.
  • Preparing CSF, Plasma, DNA and blood for shipment.
  • Organize and summarize data using scientific and statistical techniques.
  • Review and Analyzing CT Scans following established protocol for project related variables and measures.
  • Assists with curation of Lab standard operating procedures (SOP’s)
  • Calendar and meeting management for Investigators related to ongoing laboratory projects.
  • Assisting in preparation of manuscripts.
  • Assisting in preparation of grants e.g. preparing figures, drafting letters from the committee, and writing project and method descriptions.
  • Participating in upkeep of lab, performs basic maintenance on laboratory equipment and reports equipment requiring repair to Senior Research Lab Manager
  • Participating in and presenting data at weekly lab meetings and journal clubs.
  • Performing other job-related duties as assigned.

A Clinical Research Coordinator II performs the duties of a Clinical Research Coordinator I (above) and may also:

  • Maintain research data, patient fields, regulatory binders and study databases
  • Perform data analysis and QA/QC data checks
  • Organize and interpret data
  • Monitor and evaluation lab and procedure data
  • Evaluate study questionnaires
  • Assist with preparation of annual review of lab
  • May assist PI to prepare complete study reports

SKILLS/ABILITIES/COMPETENCIES REQUIRED: 

  • Careful attention to details
  • Good organizational skills
  • Ability to follow directions
  • Good communication skills
  • Computer literacy
  • Working knowledge of clinical research protocols
  • Ability to demonstrate respect and professionalism for subjects’ rights and individual needs

The Clinical Research Coordinator II should also possess:

  •  Ability to work independently and as a team player
  • Analytical skills and ability to resolve technical problems
  • Ability to interpret acceptability of data results
  • Working knowledge of data management program

EDUCATION: 

  • Bachelor’s degree required. 

EXPERIENCE: 

  • New graduates with some relevant course/project work or those without any prior research experience will be considered for the Clinical Research Coordinator I position outlined above. 
  • Those with a minimum of 1-2 years of directly related work experience will be considered for a Clinical Research Coordinator II position. 


 

SUPERVISORY RESPONSIBILITY (if applicable): 

  • A Clinical Research Coordinator I will not have any supervisory responsibility. 
  • A Clinical Research Coordinator II may assist with the training and orientation of new staff members.
  • A Senior Clinical Research Coordinator may assist with supervising lab staff and will assist with the training and orientation of new staff members.