Jonathan Rosand, MD, Msc
Jonathan Rosand is a clinician-scientist with expertise in genetics. He oversees all of the research conducted by the group and is the founder of the International Stroke Genetics Consortium. Dr. Rosand has devoted his professional life to the care of patients with the most devastating brain injuries and to reducing the impact of these injuries through his research. He can be found in the hospital, in his laboratory, at the Kistler Research Center or at the Broad Institute. Complementing his research and patient care, Dr. Rosand is a leader, mentor and teacher. At MGH he serves as Chief of the Division of Neurocritical Care and Emergency Neurology, and Medical Director of the Neurosciences Intensive Care Unit. He is Professor of Neurology at Harvard Medical School and an Associate Member of the Broad Institute. The founding director of both the ABMS-accredited vascular neurology training program and the UCNS-accredited neurocritical care training program at Harvard, Dr. Rosand has served as teacher and mentor to a generation of vascular and critical care neurologists.
A full list of publications from Dr. Rosand can be found here.
Chris Anderson, MD, MMSc
Dr. Anderson is a Neurocritical Care physician with research expertise in the medical genetics of complex diseases, specifically ischemic and hemorrhagic stroke. His career research goal is to use computational, genetic, and epidemiologic tools to derive new information about the mechanisms underlying cerebrovascular disease, and to use this information to drive improvement in stroke care through the identification of novel treatment targets and implementation of precision strategies for primary and secondary prevention.
A full list of Dr. Anderson’s publications can be found here.
Christina Kourkoulis is the Senior Research Lab Manager for the Rosand and Anderson Labs as well as the Aging and Brain Health Research (ABHR) Group led by Dr. Biffi . She handles all administrative, safety, regulatory and financial duties for the labs. Christina received her bachelor’s degree in Marine Biology from the University of Massachusetts at Dartmouth in 2002. Her previous research and management experience has been with sleep and circadian rhythms at Boston University Medical School as well as genetics of brain malformations at Children’s Hospital Boston.
Katrina Screen is Jonathan Rosand’s Office/Project Manager. She serves as the point of contact for Jonathan in both the Rosand Lab and in the Neurosciences Intensive Care Unit. Katrina received her Bachelor’s degree in Communications and Art History at the University of Massachusetts, Amherst and her Master’s in Counseling Psychology from Assumption College.
Alessandro Biffi, MD
Alessandro Biffi is Assistant Director of the Behavioral Neurology and Neuropsychiatry Fellowship and Assistant in Neurology in the Department of Neurology at MGH. He is also an Instructor in Neurology at Harvard Medical School ,Affiliated Faculty at The Broad Institute of Harvard and MIT and a Researcher in the Rosand Lab.
Alessandro received his MD degree from University of Milan-Bicocca (Milan, Italy), and completed his residency in Neurology with the Massachusetts General Hospital / Brigham and Women’s Hospital / Harvard Medical School training program. He joined the Rosand Lab in 2008, and his research initially focused primarily on genetic association studies of ischemic stroke, intracerebral hemorrhage and Alzheimer’s disease. He later endeavored to incorporate genetic risk factors with clinical data and imaging markers to comprehensively explore the biological underpinnings of cerebrovascular and neurodegenerative disorders.
Alessandro is the current recipient of an NIH-NINDS Research Education R25 grant for his project titled “Integration of Clinical, Neuroimaging and Genetic Information for Prediction of Cognitive Decline after Intracerebral Hemorrhage”. His current research efforts focus on developing precision medicine tools for prevention and treatment of cognitive decline in cerebrovascular and neurodegenerative disorders, with particular focus on Vascular Cognitive Impairment. He is also leading investigative efforts into the neuropsychiatric comorbidities associated with cerebrovascular disorders, with particular focus on late-life onset depressive disorders caused by cerebral small vessel disease. Alessandro is also involved in investigational and clinical efforts focused on maintenance and recovery of cognitive well-being, as part of the upcoming Massachusetts General Hospital Brain Health Initiative.
Sandro Marini, MD
I was born and raised in Pistoia, Italy, where I’ve done most of my studies, including high school, where my strong interest in science began. Following my university studies, I graduated from medical school cum laude with a thesis on the genetics of memory at the University of Florence in 2009. I started the neurology residency right after at the same University, graduating cum laude in 2015. I was trained in the stroke unit and I was responsible for clinical assessment, neuroimaging and neuropsychological evaluation in a study on the risk factors of cognitive disorders in the elderly. More recently, I spent one semester at the University of Geneve, Switzerland, where I dedicated myself to advanced computational neuroimaging, studying functional and structural connectivity measures in vascular cognitive impairment. Finally, I spent six months in Albuquerque (NM) where I had the opportunity to become more familiar with molecular mechanisms of the white matter injuries, commonly seen in elderly patients. Cerebrovascular disease and aging brain are my main interests to explore while in the Rosand Lab.
Katherine Crawford, BS
Katherine Crawford is a Research Coordinator at the Rosand Lab of Massachusetts General Hospital. She works with international investigators and laboratories to coordinate the flow of genomic data and analyses for work in Intracerebral Hemorrhage (ICH). Furthermore, Katherine convenes the International Stroke Consortium. Katherine received her Bachelor of Science from Cornell University in Biology with a concentration in Genetics, Genomics, and Development and a minor in English.
Umme Lena, BA
Umme Lena is a Research Coordinator in Dr. Rosand’s Lab. Umme collaborates with investigators and research coordinators to analyze genomic data on the underlying causes of intracerebral hemorrhage. She received her Bachelor of Arts from Mount Holyoke College in Biology and English minor. She has written a thesis on gecko morphology and also done research on peripheral circadian rhythms in mice liver.
Joel Salinas, M.D., M.B.A.
Joel is a fellow in behavioral neurology and neuropsychiatry with expertise in epidemiology and social determinants of stroke outcomes. His long-term goal is to develop and deploy strategies to prevent the development of devastating chronic brain disease. His current work in the lab focuses on investigating predictors and modifiable risk factors of age-related neurologic disease and its sequelae using large epidemiologic cohorts, including the Women’s Health Initiative and the Framingham Heart Study. After graduating from Cornell University, Joel completed medical school at the University of Miami Miller School of Medicine followed by neurology residency at the Massachusetts General Hospital and the Brigham and Women’s Hospital.
Andrea Morotti, MD
Andrea spends the majority of his time at the National Neurological Institute C. Mondino in Pavia, Italy serving as a Stroke Attending. The main focus of his research revolves around ICH expansion and in particular, non-contrast CT markers of hematoma growth in hopes to elucidate the relationship between inflammation, secondary complications and outcome in ICH patients. A long term goal is to create an ICH registry in Pavia, Italy.