More than 60% of individuals die or are left with severe disability following intracerebral hemorrhage. The accurate prediction of outcome is therefore essential to help families of affected individuals decide on goals of care, as they consider whether their loved one would choose to survive. Prior to the publication of this study, there were no validated scores to predict functional recovery. Widely used scores simply predicted mortality. Furthermore, the majority of scores had been developed in cohorts in which withdrawal of care by family members was common, but not accounted for in the development of the score itself. Thus the effect of withdrawal of care on the accuracy and reliability of the scores could not be assessed. The FUNC score was developed to assess the probability of returning to functional independence. We developed and validated it in patients who survived, under the assumption that we could be relatively certain that no patients who ultimately survived had their care withdrawn.  Easily calculated using our website tool and incorporated into a variety of iPhone apps (e.g. Neuro Tool Kit), the FUNC score is now used throughout the world in the care of patients with ICH.

Related Publications

  1. Burden of Blood Pressure-Related Alleles Is Associated With Larger Hematoma Volume and Worse Outcome in Intracerebral Hemorrhage.

    Falcone GJ, Biffi A, Devan WJ, Brouwers HB, Anderson CD, Valant V, Ayres AM, Schwab K, Rost NS, Goldstein JN, Viswanathan A, Greenberg SM, Selim M, Meschia JF, Brown DL, Worrall BB, Silliman SL, Tirschwell DL, Rosand J. Burden of Blood Pressure-Related Alleles Is Associated With Larger Hematoma Volume and Worse Outcome in Intracerebral Hemorrhage. Stroke 2013;44(2):321-6. PMID: 23321443; PMCID: PMC3560332

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  2. Statin use and outcome after intracerebral hemorrhage: Case-control study and meta-analysis

    Biffi A, Devan WJ, Anderson CD, Ayres AM, Schwab K, Cortellini L, Viswanathan A, Rost NS, Smith EE, Goldstein JN, Greenberg SM, Rosand J. Statin use and outcome after intracerebral hemorrhage: Case-control study and meta-analysis. Neurology 2011, May 3;76(18):1581-8. PMID: 21451150; PMCID: PMC3100126.

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  3. Anemia and hematoma volume in acute intracerebral hemorrhage

    Kumar MA, Rost NS, Snider RW, Chanderraj R, Greenberg SM, Smith EE, Rosand J. Anemia and hematoma volume in acute intracerebral hemorrhage. Critical Care Medicine. 2009;37:1442-47. PMID: 19242340.

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  4. Prediction of Functional Outcome in Patients with Primary Intracerebral Hemorrhage: The FUNC Score

    Rost NS, Smith EE, Chang Y, Snider RW, Chanderraj R, Schwab K, FitzMaurice E, Wendell L, Goldstein JN, Greenberg SM, Rosand J. Prediction of Functional Outcome in Patients with Primary Intracerebral Hemorrhage: The FUNC Score. Stroke. 2008;39:2304-09. PMID: 18556582.

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